SubtiBank SubtiBank
Version comparison:

2019-02-24 17:59:342025-05-09 16:07:31

locus

BSU01770

BSU_01770

outlinks

bsu

BSU01770

BSU_01770

The protein

Catalyzed reaction/ biological activity

alpha-D-glucosamine 1-phosphate --> D-glucosamine 6-phosphate (according to Swiss-Prot)

inhibition of [[protein|CdaA]] activity (demonstrated in S. aureus) [pubmed|30668586]

D-glucosamine 6-phosphate --> α-D-glucosamine 1-phosphate (according to UniProt)

inhibition of [[protein|CdaA]] activity under conditions of osmotic stress (demonstrated in L. monocytogenes ) [pubmed|32250026]

The protein

Protein family

phosphohexose mutase family [pubmed|15238632]

phosphohexose mutase family (with [[protein|PgcA]], [pubmed|15238632])

Biological materials

lacZ fusion

GP1340 (cat) based on [[protein|pAC6]], available in [SW|Jörg Stülke]'s lab

GP1340 (cat) based on [SW|pAC6], available in [SW|Jörg Stülke]'s lab

References

Original publications

17726680, 17218307, 8550580, 10231382, 10671448, 20097688, 20525796, 21685296, 23192352, 22211522, 26240071, 26585449, 28516784, 15238632, 30668586

32250026, 17726680, 17218307, 8550580, 10231382, 10671448, 20097688, 20525796, 21685296, 23192352, 22211522, 26240071, 26585449, 28516784, 15238632, 30668586, 31589605, 32250026

The protein

additional information

overexpression of [[protein|GlmM]] suppresses the synthetic lethality of [[gene|pgcA]] and [[gene|glmR]] inactivation [pubmed|31589605]